Biography:

Hideo Nakayama was the Chief Dermatologist in Tokyo Saiseikai Central Hospital from 1970 to 1995. He was the Visiting Lecturer of Keio University, School of Medicine, from 1973 to 1995, Chief Dermatologist and Allergologist at Nakayama Dermatology Clinic from 1995 to 2015. He has graduated from Keio University, School of Medicine in 1961. Currently, he is the Advisor Doctor in Meguro Chen Dermatology Clinic (Tokyo). He has discovered new allergens, such as palladium,benzyl salicylate, R-219 (D&C R-31), ylang-ylang oil, α-acaridial, etc., and developed new treatment systems by allergen control with pigmented cosmetic dermatitis,
textile dermatitis, dental metal allergy and atopic dermatitis

Abstract:

Contact allergens had been investigated during the 1970s and 1980s, resulting in the discoveries of various fragrant materials, such as benzyl salicylate, hydroxycitronellal, Jasmin oil, ylang-ylang oil, sandalwood oil, etc. Other common sensitizers included RedNo.31 / Phenyl azo naphthol, and Yellow No.11. Some cases of lupus erythematosus were due to Yellow No.11, a primary sensitizer. After millennium, the incidence of these allergens decreased considerably, instead, contact allergy to metals in the cosmetics has increased. Such metals come from the dish for foundation, scrub-ball for sunscreens, eyelash curlers, etc. The caution for these metals is needed hereafter.