International conference and exhibition on Cosmetic Dermatology and Hair Care December 07-08, 2015 Philadelphia, USA

Biography:

Mark Schafer is President of Photosonix Medical, and has served in senior roles for several ultrasonic device companies. He has over 20 peer-reviewed publications, 21 patents, and is a Fellow of the AIUM and the ASA. Mark holds a BSEE from MIT and a PhD from Drexel University. Tessie McNeely is an expert in infectious disease and biofilms. She served in senior scientific roles at Merck, where she earned multiple awards for scientific contributions, and was Principal Scientist for the development of an acne vaccine. She holds a BA from Berea College and a PhD from UNC at Chapel Hill.

Abstract:

Bacteria preferentially grow as colonies surrounded by a complex matrix, together called a biofilm. When bacteria form biofilms, they become extremely difficult to treat because they have a physical barrier and exist in a low metabolic state. Recent data demonstrates that P. acnes, which causes chronic acne, forms biofilms which may contribute to the limited efficacy of existing treatments. PhotoSonix Medical, Inc. has developed CLENS™ (Coincident Light Energy and Non-focused ultrasound), a patented energy-based therapy which synergistically combines light and ultrasound energy to treat chronic acne. Ultrasound energy mechanically stresses P. acnes bacteria, causing them to boost their metabolism and become susceptible to treatment. Therapeutic light targets porphyrin, creating reactive oxygen products which are toxic to bacteria. The combined treatment may also enhance healing because ultrasound increases blood flow and tissue remodeling, and light reduces chronic inflammation. To date, both laboratory and in-vivo studies have been conducted. Laboratory testing on P. acnes biofilms demonstrated that the CLENS combination of light and ultrasound caused 90% and 99.94% cell death following 5 min, and 30 minutes of CLENS exposure respectively. Under the same conditions, erythromycin had minimal bactericidal effect. In-vivo data has shown over 90% reduction in skin surface bacteria in as little as 10 minutes. A reduction in skin bacteria of greater than 90% is a validated surrogate for clinical efficacy. Importantly, efficacy required the simultaneous application of both energies. CLENS may offer a new therapeutic option to chronic acne patients without use of antibiotics.

Biography:

Róbert SzipÅ‘cs received the M.Sc. degree in electrical engineering at the Technical University of Budapest, Hungary, in 1987 and his Ph.D. degree in physics at the University of Szeged, Hungary, in 2001. From 1987 to 2013, he has been working for the Institute for Solid State Physics and Optics of the Wigner Research Center for Physics of the Hungarian Academy of Sciences. From 1997, he is the managing director of R&D Ultrafast Lasers Ltd. He is the author of nearly 50 articles, and a few patents. His research interests include dispersive properties of optical coatings and fibers, ultrafast solid state and fiber lasers, nonlinear microscopy and its applications in dermatology, neuroscience and nanomedicine. He is a member of the Optical Society of America.

Abstract:

Nonlinear microscopy, such as two-photon excitation fluorescence microscopy (2PEF), and second-harmonic generation (SHG) microscopy is being increasingly used to perform in vivo studies in dermatology. These techniques enable us to investigate the morphology and monitor the physiological process in the skin by the use of femtosecond lasers (such as a broadly tunableTi-sapphire laser) operating in the near-infrared spectral range (680-1060 nm). Recent years brought revolutionary progress in development of femtosecond pulse, all-fiber laser oscillators and amplifiers being suitable for nonlinear microscopy. Fiber lasers are of great interest not only because of their considerably lower price but the ease with which they can be combined with endoscopy, which would greatly increase the utility of nonlinear microscopy for pre-clinical applications and tissue imaging. In our presentation we introduce our novel, handheld nonlinear microscope system named FiberScope comprising a ~2MHz repetiton rate Yb-fiber laser as a pulsed light source for nonlinear imaging. Among others, our novel microscope system is capable of high quality in vivo 3D SHG imaging of the collagene content of murine skin at average power levels as low as ~5 mW, which value is measured directly above the skin. (Note this power level corresponds to that of a laser pointer.) Using SHG imaginging of the collagene, we investigated and followed the effects of obesity on dermal collagen alterations for instance. Additionally, using 2PEF microscopy, we could also visualize and monitor the in vivo the uptake of Alexa Fluor 546 labelled nanomedicine by Langerhans cells for 24 hours.

Biography:

Andrej Petrov 44 years old. Dermatologist, Head of Dermatology Dpt. in Acibademsistina Hospital. Medical faculty and specialization in dermatology finished in Skopje and Master Degree at University in Belgrade. Finishing PhD thesis until the end of 2015. Principal investigator in ongoing multicentre study CHS1420-02. Speaking English, French, Italian.

Abstract:

Introduction: Fractional carbon dioxide laser is used in the treatment of many dermatological diseases, as well as in several aesthetic procedures. Main objectives: of the study are: to confirm the efficiency and safety of the fractional CO2 laser in skin renewal, and to check the possibility of having a synergistic effect in patients who besides carbon dioxide laser are treated with PRP /platelet-rich plasma/ too. Material and methods: The study was prospective, case control study and was carried out at the Department of Dermatovenerology, in the period from 2013 - 2015, with total number of 232 patients included in the study. The patients were divided into three groups. The first group (Examined Group 1) included 107 patients treated with fractional CO2 laser (Lutronic eCO2) as month therapy. The second group /Control Group/ covered 100 patients treated with neither laser nor plasma in the same period but subjected to local therapy with drugs or other physio-procedures under the existing protocols for treatment of certain diseases. The third group /Examined Group 2/ treated 25 patients with combined therapy of CO2 laser and PRP in the treatment of facial rejuvenation or treatment of acne scars. Inclusive criteria for entering the study are patients who have one of the following clinical conditions: acne and residual efflorescence of acnes, scars from different backgrounds, stretches, photo damaged skin, hyperpigmentation, xantelasma, syringoma, viral warts. Exclusionary criterion in the study is the use of: oral retinoids in period of 6 months prior to the laser treatment, use of anticoagulation therapy, age under 18, presence of systemic diseases in the patient, using artificial light sources, sauna, during the treatment, use of fillers,, pregnancy andherpes viral skin infections. Patients in the second group (CG) undergone therapeutic modalities depending on the diagnosis of the disease, and according to the existing protocols for certain diseases. For patients with acne scars and patients who undergone rejuvenation, the comparison was made with retinoids, topically applied to the skin. For patients with viral diseases of the skin, comparison was made with standard, the most widely used method for treatment of these diseases – cryotherapy. The results and conclusion: Fractional CO2 laser used in treatment of patients with acne scars, is an effective and safe method that causes statistically significant better effect of the treatment, greater patients’ satisfaction, minimal side effects and statistically better response to the therapy. In the treatment of skin rejuvenation, the laser treatment is effective and safe, causing statistically significant higher satisfaction in relation to the control group of patients. Satisfaction with the treatment in patients undergoing rejuvenation is greater than in any of the examined groups. Fractional carbon dioxide laser is safe to use in treatment of viral diseases of the skin and mucous membranes, condylomas and warts, without distinct side effects and discomfort in the treated patients. However, the effect of the therapy and patients’ satisfaction, and also evaluation by the doctors is statistically lower in relation to the control group of patients. In all three indicative subgroups of the laser examined group (acnes, rejuvenation, viral warts) there are no statistically significant mutual differences in relation to the laser treatment, i.e. it is equally efficient. The combined laser treatment using platelet-rich plasma versus laser monotherapy shows greater cumulative assessment of the effect of applied treatment, but without statistical significance.

Biography:

Dr. Arterbery is a radiation oncologist and graduate of the University of Michigan Medical School. She completed her residency at Memorial Sloan Kettering Cancer Center in Manhattan. She has an interest in skin care and is relationship to damage from cancer treatment and was one of the principals in bringing BIAFINE to the US market from France to treat radiation dermatitis. She has a passion to help women improve and delay the aging process and reduce the risk of cancer through natural cosmetics.

Abstract:

Although sun safety and sunscreen had been promoted since the 1940s, studies have shown insufficient implementation by end users thus decreasing overall and efficacy of the benefit of these products. Dermatologists had been faced with an increasing incidence of skin cancer in the large cohort of high-risk patients with irreversible histories of significant sun damage. Skin cancer in the US is more common than other all other cancers combined. Over 100,000 new cases of melanoma and one million new cases of non-melanoma skin cancers are expected to occur per years. Both types are associated with significant morbidity and high healthcare cost. Chemoprevention is a pharmacological invention that prevents, arrests and reverses carcinogenesis. Primary chemoprevention decreases the risk of malignant cancers and it’s important for high-risk patients. There is an increase interest in skin care products that actually can naturally provide decreased risk of skin cancer or assist in the reversal of the UVA damage. In this talk, we will discuss oral and natural retinoids, statins, fern extracts, botanicals, green tea, resveratrol and antioxidants, flavones and nutraceuticals that can be incorporated into anti-aging products to potentially increase the antimutagenic potential and offer a cosmetic benefit as well as a potential long-term benefit for reduction of skin cancer.

Biography:

Dr. Baum has built a reputation as a cosmetic dermatologist by providing leading-edge treatments, dedicated and personalized patient care, and excellent aesthetic results. Dr. Baum is often asked to share her expertise to the English and Spanish-speaking media about the latest advancements in skin care technologies. She has collaborated in several publications, in world re-known dermatological journals and books with her research. Dr. Baum remains committed to the highest standards of patient care and is actively involved in several professional organizations. Dr. Baum is proud to treat patients of all ages and skin types, and has experience in cosmetic, general, surgical and pediatric dermatology. Dr. Baum is a proud alumna of the University of Miami with a Bachelor of Science in neuroscience Summa Cum Laude, received her medical degree from the Nova Southeastern University College of Osteopathic Medicine. Upon graduation, Dr. Baum completed an internship in Westchester Hospital, as well as a residency in dermatology at the NSU COM Larkin Community Hospital, where she was chief resident during her last year. She is married with 2 children, and enjoys spending time with her family.

Abstract:

Background: Cutaneous biopsy sites are often difficult to discern or are frequently misidentified when patients present for treatment of skin cancers. This frustrating situation can lead to delays in treatment and wrong site surgeries. Current methods aiming to prevent this situation are not perfect. Objective: This study seeks to determine the efficacy of ultraviolet-fluorescent tattoos in facilitating the correct identification of suspected nonmelanoma skin cancer biopsy sites. Methods: In this prospective cohort, 51 shave biopsy sites were tattooed with ultraviolet- fluorescent ink in a series of 31 patients suspected of having a cutaneous malignancy. At the time of follow up, the ability of the patient and the physician to identify the correct site with and without ultraviolet illumination of the tattoo was recorded. Visibility of the tattoo was graded before and after treatment. Results: Patients could not positively identify their biopsy site in 35% of cases. In 7% of cases, physicians could not confidently identify the site without the aid of ultraviolet illumination. In conjunction with tattoo illumination, physicians confidently identified the site in 100% of the cases. No adverse events occurred. Conclusion: Ultraviolet-fluorescent tattoos offer a safe and reliable means of accurately marking cutaneous biopsy sites. Keywords: Ultraviolet tattoo; nonmelanoma skin cancer; biopsy site; Mohs micrographic surgery

Biography:

Abstract:

Aim: The aim of this study was to investigate the epidemiologic profile, to describe the clinical sign and to evaluate the treatment options. Methodology: It was a prospective study from January to December 2014, respectively. It was carried out using 26 patients for seborrhea dermit. Their ages ranged from 10 to 70 years old, inclusive of young adults. The sex rate (H/F) =0.6, with females being dominant during the study. The frequency of seborrhea dermit was represented at 2.98% of consultation in our department. During the study, the main signs were erythema (42,62%) and squamous (42,62%). The level of the sum of the topography was 3,617. About half of the patients lived with HIV(4,330%). The treatment of seborrhea dermit can be local, general or associated. All the patients received maximum attention during the study and profit from a local treatment was favorable at 7,692%. At the end of the study, an increase in the frequency of the seborrhea dermit was observed, with the advent of HIV.

Biography:

Foulematou Soumah, Master in Dermatology in Tongji medical college of Huazhong university of science and technology , Wuhan China. Her research has focused on Dermatology

Abstract:

The aim of the study was to describe the side effects of the depigmentation on the skin in the Guinean population. It was a retrospective on the cross sectional carry out from January 2012 to December 2014 inclusively. The study was based in the 276 patients admitted in our department .The mean age is 25 years , their age range from 18 to 30 years. The main clinical signs observed was; whitness of the skin (100%), loss of elasticity (87%), acne (35%), Burn of the skin (85%), followed by the squamous erythema (15%), cancer of the skin. The side effects of the depigmentation are numerous, however in the African context especially in the tropical countries, are characterize by the appearance of cancers of the skins.

Biography:

Yan ding working in the Department of Dermatology, Maternal and Child Health Care Hospital of Hainan Province, Haikou 570206, Hainan, China. Her research has focused on Dermatology, Nephrology, Internal Medicine (General Medicine)

Abstract:

One of the major disease manifestations of systemic lupus erythematosus (SLE) is lupus nephritis (LN),and the underlying mechanisms are not yet understood. Epstein-Barr virus (EBV) reactivation was associated with the induction of SLE, with EBV-encoded latent membrane protein1 (LMP1) plays a vital role in this process. Although it was reported that LN was associated with LMP1, most of these results are from patients with ages differed greatly (range, 10-56 years). Given the increased prevalence of EBV infection in young patients, we focused on the association of LN and LMP1 expression in the renal tissues of young patients (range, 6-16 years) in this study. We found that the positive rate of LMP1 in the renal tissues was significantly higher in patients with LN compared with control (P<0.001), which is consistent with the previous reports. The positive rates of LMP1 were similar between the patients of initial onset and relapse, and there was no detectable difference between the patients with and without concurrent infection (P>0.05). However, we reported for the first time about the positive correlation of LMP1 with classification of LN. The proportion of young patients positive for anti‑Sm antibody was significantly higher in the LMP1 positive group compared with the LMP1 negative control (P>0.05). These results indicate that EBV infection in the renal of young patients may lead to the increased severity of LN, and the expression of anti-Sm is likely contributed to this process. Keywords: SLE, LN, EBV, LMP1

Biography:

Terry Henry is a Medical Practice Wellness Integration Consultant with nutraMetrix, supporting hospital systems and a wide spectrum of licensed health professionals, from dermatologists to bariatric surgeons. He is a Certified Meditation Instructor, Reiki Master and graduate of Harvard Business School and Williams College.

Abstract:

Oxidative stress and inflammation have been shown to be both a primary and aggravating cause of skin damage and aging. Oxidative stress, either environmental or intrinsic, may have complex metabolic or subclinical root causes, aggravated by effects of medication, poor diet, malabsorption or poor nutrient retention/bioavailability. It has been shown that free radical damage and Nutrient imbalance can impair skin physiology and accelerate functional decline, if the body’s natural antioxidant defense system And immune function become overwhelmed. We will explore several integrative health & nutrient therapy interventions, and Cosmaceutical advances impacting metabolic/psychophysiological regulation, skin health and resilience, and well as opportunities to optimize patient wellness.

Biography:

Bojana Matovski - The “Beauty Doctor” holds a Doctor of Medicine from the University of Belgrade, the capital of former Yugoslavia. She has studied with such leading providers as plastic surgeon, Jadran Dondic, Doc.dr.sci.med. Nenad Stepic; Zoran Stojcic, a maxilla-facial surgical specialist who has used Pluton Electronic at the Mayo Clinic; and at Jacksonville University Hospital, as well as with Zarko Borovic of Orea – Special Hospital for Plastic Reconstruction and Aesthetic Surgery. After completing this extensive training, she is internationally certified to educate/ train others in the use of all Pluton Electronics devices which are used in conjunction with hospitals specializing in aesthetic plastic surgery. Her motto at work is “rejuvenate the skin – hold up aging!” Because of her outstanding achievements Worldwide, Who’s Who in American Education 2012-13, recognized her, as Owner, Trainer, and Educator of executives, professionals and entrepreneurs, and in May 2012, the National Association of Professional Women named her Woman of the Year 2012/2013.

Abstract:

3rd Generation Radio Frequency technology is the world’s most advanced Radio Frequency technology. Clinically proven and used successfully by physicians, aestheticians and clinics around the world, it regenerates collagen, tightens and tones the skin, improves the appearance of cellulite and reduces body circumference. Three Polar Technology is used to simultaneously heat deep and superficial layers. This focused, selective deep heating stimulates the body’s natural skin renewal process, tightening existing collagen fibers and augmenting new collagen generation. It also accelerates fat metabolism to cause fat cells to shrink, improving cellulite appearance and treating localized bulges and fat deposits in many areas of the body. Treatment provides immediate visual effect and a long-term result. The immediate visible effects are a smoother, tightened appearance and texture – visible from the very first treatment. The long-term effects of the deep heating accelerate the metabolism of fibroblasts, which produce collage, augmenting new collagen generation. Newest Quadruple Radio Frequency is based on active’s BRF Technology (burst Repetition Frequency), combined with real-time continuous thermal skin monitoring. This technology provides treatment effectiveness and side effect free treatments. Quadro Polar RF is designed to produces skin-tightening: it also removes unwanted fat and toxins. The new treatment is based of two RF effects: Fat cells drainage/breakage and skin rejuvenation and lifting. With RF energy, we can increase the metabolism of the connective tissues and break/shrink the fat cells trapped inside them resulting in a smooth, cellulite free skin. Quadro Polar RF penetration through the skin with a limited influence on the epidermis. The procedure is painless, even pleasant: there is a feeling of warmth. Ultrasound Cavitation - “Liposuction without Liposuction” Cavitation implies the use of an appliance equipped with a hand piece which is placed on the skin, targeting fat deposits, so that the fat cells are dissolved by using special manipulation technique. Over a more or less short period of time, cavitation allows to get amazing results such as the reduction of total removal of cellulite and fat in specific areas. This is exactly what Re-Age offers to its clients.

Biography:

Dr. Meena Singh is a board-certified dermatologist and dermatologic surgeon currently practicing in New York City and Kansas City. She attended Harvard Medical School, trained at the Mayo Clinic, and completed a surgical fellowship in New York City, in which she became trained in Mohs Micrographic Surgery, as well as cosmetic dermatology procedures, such as Botox, lasers, and fillers. She also completed a fellowship with the International Society for Hair Restoration Surgery under world-renowned surgeon Dr. Marc Avram, and was trained in all hair transplantation techniques, including strip excision and manual/motorized/robotic follicular unit extraction, as well as transplanting into scarring alopecias. She also specializes in medical treatments for hair loss of all types. Dr. Singh also has an interest in treating ethnic skin/skin of color. Dr. Singh has performed clinical trials in laser hair stimulation, as well as studies in hair transplantation for scarring and non-scarring forms of hair loss. She has also performed investigative studies on skin cancer in transplant recipients, as well as tissue engineering. She has numerous publications in many peer-reviewed dermatology journals, book chapters, and has been published in the New England Journal of Medicine. She is a reviewer for the Journal of Cosmetic Dermatology and the Dermatologic Surgery journal. She has had numerous TV appearances and her blog articles have also been published in online and print periodicals. Dr. Singh has also been featured on the cover of New York Times.

Abstract:

20- 30% of all women suffer from female pattern hair loss (FPHL) in the US. Society expects to see hair thinning and hairline recession in men; however, it is less socially acceptable when it occurs in women. Fortunately, most women can be aided with a combination of both medical and surgical therapies. Minoxidil is the only FDA approved treatment for at this time. In the majority of women, it stops progression of the disease and can rethicken hair. Many women with FPHL are candidates for hair transplantation. With the use of follicular unit transplantation with smaller 1-4 follicular unit grafts, very good cosmetic, natural-appearing results can be achieved. Consultation for hair transplantation with a female patient differs somewhat than with a male patient. Because of the nature of FPHL, the patient is often more concerned about the ‘see-through’ nature of the scalp, as opposed to regression of the hairline or loss at the vertex scalp. They have a more unpredictable donor area. They can demonstrate telogen effluvium postoperatively. In addition, it is important to perform a detailed scalp examination and consider further labs and potentially scalp biopsy to differentiate FPHL from telogen effluvium or scarring alopecias. In consultation, the patient should be made aware that net cosmetic outcome and density will reflect the amount of hairs transplanted minus the ongoing hair loss. In addition, placing the hairs predominantly in the frontal scalp, as opposed to diffusely spreading it throughout the involved areas will lead to a better cosmetic outcome. The main procedural consideration for the surgery is that transplanted hairs will be placed in between existing hairs. The talk will begin with a general introduction, review differences between females and males, as well as technical considerations. The majority of the talk will be case based.

Biography:

Omid Arjmandi-Tash got MSc degree in Chemical Engineering from the University of Tehran. Currently he is a Research Associate at the Department of Chemical Engineering, Loughborough University. He is carrying out a joint research with Proctor & Gamble, USA. He has already published around 10 papers in highly rated scientific

Abstract:

Hair care products are expected to wet well human hair, even when the hair is hydrophobic. Thus, wetting properties of human hair are very important, as they influence consumer satisfaction with the products. Wettability of a hair tress is an important characteristic. The wetting behavior of polymer solutions on hair is less studied than surfactant solutions. The wetting of hair tresses by aqueous solutions of commercially available polymers AculynTM 22 (A22) and AculynTM 33 (A33) has been investigated. Both experimental studies and numerical simulations of behavior of polymer solutions and foams on tresses of human hair has been investigated including drainage of foams produced from solutions of those polymers and interaction of foams with hair stresses are presented. Both A22 and A33 solutions demonstrate well pronounced shear thinning behavior. Initial contact angle of the A22 and A33 solutions on undamaged hair tresses is about 100 o. The A22 droplets remained on the hair tress after spreading for at least half an hour. However, a fast penetration of the A33 droplet inside the hair tresses was observed when advancing contact angle in the course of spreading reaches a critical value of about (60 o). Pure solutions of A22 and A33 have higher initial contact angle and longer penetration time on hair tresses compared with the solutions containing i-propanol or sodium dodecyl sulphate. The results demonstrate that wetting kinetics of the polymer solution on hair tresses drastically different depending on the formulation and can vary from a rapid imbibition to a spreading only.

Biography:

Dr. K. Ravi did Post graduate in Siddha system of Medicine in The Tamil Nadu Dr. MGR Medical University, Chennai, India and he has been selected by the union public service commission and appointed as a Medical officer in the Central Government Dispensary and promoted to Chief Medical officer and served 20 years and now working as Joint Adviser (Siddha) in the Ministry of AYUSH, Government of India, New Delhi. He has published and presented 11 papers in reputed journals and conferences.

Abstract:

Psoriasis is a common life long, genetic, autoimmune skin disease characterized by well circumscribed areas of thick, red, scaly skin and From the Greek “psoros” meaning “rough, scabby, itch. In Siddha System of medicine Psoriasis is termed as Kalanchakapadai.Psoriasis is very well treated in Siddha System of Medicine for so many years and found patient is very much relieved from the thick, red, scaly skin and the recurrence is very much postponed and the patient may also have normal skin for many years. Vetpali Thailam (777 Oil) is a boon to treat psoriasis Patients for getting relief from the unexplained sufferings of the disease.

Biography:

Manager of scientific department, research and development,biologist and biochemist at Cepigene. Her research focus on what causes the disorders on hair and scalp, hair loss and dandruff, and also Research on cosmetics products such as anti wrinkles and actives

Abstract:

Epithelial’s stem cells are located in histological area called bulge in the middle part of hair follicle between arrector pili muscle and sebaceous gland which their potential to differentiate to variety of cells such as chondrocytes, osteoblasts, adipocytes, melanocytes, etc., is confirmed via several researches; as well as there is non-invasive method to extract hair follicle to culture organ for isolation of its stem cells, regarding the effect of some ingredients such as different herbal extracts and growth factors on aforementioned stem cells proliferation makes them suitable for tissue engineering. If these cells keep their proliferation potential in presence of such ingredients it can be a step to use them instead of other mesenchymal stem cells derived from adipose tissue or bone marrow to supply the required cells in scalp and skin area as well as in medical cell therapy; in this research the potential of proliferation of human hair follicle mesenchymal stem cells (hHFMSCs) is evaluated before differentiation in presence of several compounds. Some hair follicle cultured for 7 days after isolation from the scalp of 3 men with average age of 35 years; the wells populated with cells which had the morphological appearance of mesenchymal cells thus they were selected and pooled after survey on their superficial markers via flow cytometry and their mesenchymal nature was approved; also their potential for differentiation to osteoblasts and adipocytes approved by real-time RT-PCR., then expanded for 7 days in 8 distinct groups in 24-well culture plates with stromal medium culture containing 10% FBS, the first group supplemented with 1 ng/ml EGF, 1 ng/ml bFGF and 1 ng/ml aFGF, second group supplemented with 1.5% aqueous extract of leaf of Rosmarinus officinalis, third group supplemented with 1.5% of aqueous extract of root of Althaea officinalis, the fourth and fifth groups supplemented like the second and third groups but 3% of abovementioned extracts, the sixth group considered as the negative control, the seventh group considered as the positive control 1 with 1.5% aqueous extract of Rosmarinus officinalis plus 1.5% aqueous extract of Althaea officinalis besides growth factors with the same concentration to group 1, the eighth group considered as the positive control 2 with 3% aqueous extract of Rosmarinus officinalis plus 3% aqueous extract of Althaea officinalis besides growth factors with the same concentration to group 1; the cells proliferation potential evaluated by BRDU Assay. The comparison of results showed that the rate of cell proliferation in first group was more than other, then the seventh and next was the eighth group then in order, fifth, third, second, fourth group and eventually the negative control. This study showed that aqueous Rosmarinus officinalis extracts may be able to regulate the out of control proliferation of MSCs which is very important to prevent scar and cheloide formation while using growth factors for wound healing. Key words: Mesenchymal stem cells, Human hair follicle, BRDU Assay, Wound healing, Scar.

Biography:

Adele has completed is Phd at the age of 26 years from University of Nigeria Nsuka and postdoctoral studies from Lagos University School of Medicine. He is the head of Department. He has published 17 papers in reputed journals he is currently serving as the head of board member of state medical council.

Abstract:

Encyclopedia of Bio analytical Methods for Bioavailability and Bioequivalence Studies of Pharmaceuticals (E-BABE). It is a unique encyclopedia involving bio analytical methods for bioavailability and bioequivalence (BA/BE) studies of pharmaceuticals for suitable method selection with thousands of combinations and searches against these methods. Most scrutinized literature was collected from different sources such as Drug bank, Medline, Pub Med. The bio analytical method assessment of the studied drug product, carried out in our laboratories, covers two aspects of evaluation. The first one is the drug in-vitro evaluation including conformity of drug active ingredient content and content uniformity employing official pharmacopoeia methods, and also the determination of the drug dissolution rate in accordance with the official methods. These tests were conducted to verify compliance of the drug product to applied quality standards. The second aspect involves biological or in vivo evaluation. This evaluation consists of microbiological assay for the label claim of the studied drug product, and development and validation of a suitable and reproducible bio analytical assay method to obtain plasma concentration-time profile. Data obtained to be employed for assessment of the drug product kinetics. Depending on the chemistry of the drug product, reversed-phase high performance liquid chromatography (RPLC) was chosen, as the analytical technique, in developing drug assay method, due to its explosive popularity for analytical separations. This choice was also due to many factors as will follow. The variation of element composition alone extends both retention and selectivity in RPLC over an extremely broad range of analytes. Practically all reversed phase separations are carried out on stationary phases with chemically modified hydrophobic surfaces. Minor variations in the surface chemistry and geometry can lead to noticeable differences in surface interactions and, as a result, to differences in chromatographic selectivity. Mobile phase (eluent) is by far the major “tool” for the control of analyte retention in RPLC. Variations of the eluent composition, type of organic modifier, pH, and buffer concentration provide the chromatographer with a valuable set of variables for successful development of a separation method. Mobile-phase pH affects the analyte ionization and thus its apparent hydrophobicity and retention. Most drug products may be ionizable, and therefore their retention is affected by the mobile-phase pH. The influence of temperature and type and concentration of organic analyte and pH modifier ionization are also related to HPLC retention. All the choices the biocatalyst has in terms of bonded phase, aqueous phase modifier, and organic modifier can have synergistic effects on the analyte retention and selectivity in RPLC. These parameters illustrating the power of the selection of the most suitable parameters for control of the analyte retention and selectivity, and therefore the choice of a better analytical assay method, in terms of the following validation parameters.

Biography:

Dr. Bharat Bhushan is an Ohio Eminent Scholar and the Howard D. Winbigler Professor in the Department of Mechanical and Aerospace Engineering. Dr. Bhushan came to OSU in 1991 after a 15-year career in industry, working primarily for IBM Almaden Research Center. A professor with diverse interests, Dr. Bhushan’s works in biomimetic interface science, surface engineering, nanotribology, and materials research. His research has focused on scanning probe techniques in the interdisciplinary areas of bio/nanotribology, bio/nanomechanics and bio/nanomaterials characterization and applications to bio/nanotechnology, and biomimetics. Dr. Bhushan spent the 2013-2014 year working as an ASME Science Fellow in Congress. His work there focused on policy and funding of various scientific government agencies, setting science and engineering goals for the country, and STEM education. Dr. Bhushan is a prolific author (h-index – 76+; ISI Highly Cited Researcher in Materials Science since 2007 and in Biology and Biochemistry since 2013; ISI Top 5% Cited Authors for Journals in Chemistry since 2011), influencing many different fields. He has authored 8 scientific books, 90+ handbook chapters, nearly 900 scientific papers, and 60+ scientific reports. He has also edited 50+ books and holds 20 U.S. and foreign patents.

Abstract:

Human hair is a nanocomposite biological fiber. Maintaining the health, feel, shine, color, softness, and overall aesthetics of the hair is highly desired. Hair care products such as shampoos and conditioners, along with damaging processes such as chemical dyeing and permanent wave treatments, affect the maintenance and grooming process and are important to study because they alter many hair properties. Nanoscale characterization of the cellular structure, mechanical properties, and morphological, frictional, and adhesive properties (tribological properties) of hair are essential to evaluate and develop better cosmetic products, and to advance the understanding of biological and cosmetic science. The tensile response of hair is of considerable interest. Another property of interest is the surface charge of hair, which has a significant effect on manageability, feel, and appearance. For this reason, controlling charge buildup to improve these factors is an important issue in the commercial hair care industry. The atomic/friction force microscope (AFM/FFM) and nanoindenter have recently become important tools for studying the micro/nanoscale properties of human hair. In this talk, we present a comprehensive review of the cellular structural, nanomechanical, and nanotribological properties of various hair and skin as a function of ethnicity, damage, conditioning treatment, and various environments1-2. Various cellular structures of human hair and fine sublamellar structures of the cuticle are identified and studied. Nanomechanical properties such as hardness, elastic modulus, creep and scratch resistance are discussed. Nanotribological properties such as roughness, friction, and adhesion are presented, as well as investigations of conditioner distribution, thickness, and binding interactions.

Biography:

Dr.V.Hari Kumar, MBBS, MS (Gen Surg.) (M.Ch Plastic) FIAGES, an Hair Transplant & Aesthetic Surgeon works as a Chief Consultant at B-Perfect Aesthetic Solutions, Banjara Hills, Hyderabad, India. He is an Asst. Professor at Deccan Medical College and passionately trains the Doctors& Surgeons in his self-chosen field of Creative Anti Ageing & Inner Cosmetics. He received Commendation Certificate (Best Doctor Award) twice during 2003-05 for his extensive Medico-Spiritual Holistic Health Service Activities to beautify not only outer but also inner Personality. He has authored three books & compiled 40 DVDs on Art & Science of Anti Ageing-Inner Cosmetics-Longevity-Holistic Living. His Enthralling & Energetic Live Telecasts & Debates in more than 30 Television Channels, on subjects like Medico-Spiritual Anti Ageing, Life Skills, Holistic Health helped many viewers especially Health & Success lovers.. His presentations in National & International Conferences and several Spirituous-Scientific publications add to his credit and are a Visiting Professor & guest speaker to many Organizations.

Abstract:

Hair restoration by Transplantation is the permanent, relatively safest solution for the baldness. Follicular Unit Extraction FUE,, being a scar less procedure is widely accepted and routinely done HT surgery by us. Easy recoveries, negligible pain, early resume to normal work are the noticeable benefits. Scar of FUT-strip method, presence of limited donor area due to final grades of baldness and previous surgery scars.. And also, in clients with tight scalp, keloid propensity, feasibility of hair from non-scalp hair bearing body areas are better suited for this procedure. Athletes, Clients of Medical tourism, who are with fear of pain & surgery, in case of OT assistant’s scarcity it works well.. Early stages of baldness requiring up to 1500 grafts are better candidates. High cost, need of high skilled surgeon, larger area of baldness requiring grafts more than 1500 are the limiting factors. BHT-Body Hair Transplantation where body and beard hair can be utilized for the crown and hair line design. Rest of the mid section and frontal forelock can be done with the permanent hair which is available from Hormone resistant existing safe donor area on the back of the head as a Day care Procedure. Combination of FUE & FUT Net yield will be more, extraction and surgeon’s time can be minimized, tension on the scar will be less and double &triple FU extraction can be done under vision. Number of sessions can be reduced and Trichophytic closure after strip favors the growth of hair on the scar line.

Biography:

Suzanne Anderer is a nationally recognized expert in permanent hair removal. In 1982, she founded Suzanne Anderer: Illinois School of Electrology (SA: ISE), an Illinois Board of Higher Education approved institution. Four years later, Professional, National Board Certification from the American Electrology Association (AEA) was granted and Suzanne became a Certified Professional Electrologist (CPE).

Abstract:

The S.I.M.P.L.E. (Sequential, Inverted, Micro-Pulsed, Led, Energy) employs AC (alternating Current), at the standard AC current cycle level produced in the United States for delivery to Consumers. The definition of the acronym is the following: S is a sequential series of heating Patterns; I refers to an inverted application, each pulse point traveling downwards to the base of the follicle; M is for micro, or the small heating patterns used in the method; P is for pulse which references the quick bursts of energy; L is for led, or the action of micro-pulses traveling downwards, contacting untreated tissue; and E is for energy, a term used to define electricity which has a heat-producing effect. These currents are not a galvanic or “blend” current; therefore it is not electrolysis. In my lecture, I would like to expound on this particular needle-type application; it is a method with heat-producing properties and the distinct benefit of micro-pulse, radio frequency (RF) contact throughout the ENTIRE dermis of each visible, hair-producing follicle. Variables such as texture of hair, stage of hair growth, endocrine and drug-induced hair growth, and skin color and type are accounted for in this method. This method is minimally invasive with shorter recovery periods and less damage to surrounding tissue. When correctly applied, permanent hair removal has been consistently observed in one application per visible hair (references and client data will be produced to support this).