Cosmetic Dermatology and Hair Care

The sunscreen agent accounts for 3% of the market value of cosmetics market in Japan (2015) and the shipment volume of 5,000 t is on the rise. In addition to skin color correction and skin care, addition of safety, whitening and anti-aging due to the effect of vitiligo problems, there is a demand for value. Normally, as a sunscreen agent, ultraviolet light scattering agent of titanium oxide or zinc oxide is used in combination with an organic ultraviolet ray absorbing agent. However, it reaches the dermal layer of the skin, and is known for skin aging, melanin pigmentation and active oxygen generation etc. There are few absorbents that can completely absorb light in the range of UVA (320-400 nm) wavelength area. So far, we have been aiming at practical application of ultraviolet absorption by a composite material of amino acid derivative Schiff base metal complex and titanium oxide. In this time, zinc (II) complexes were employed. Structural and chemical studies on the complexes will be presented. In addition, molecular design process using the related copper (II) complexes will be also mentioned in the keynote lecture.