Day 2 :
Keynote Forum
Kuniyoshi Kaseda
Saravio Central Institute, Japan
Keynote: Hot springs energize hair follicle dermal papillae
Time : 9:00
Biography:
Kuniyoshi Kaseda had completed his PhD at the age of 28 years from the Kyushu Institute of Technology and postdoctoral studies at the National Institute of Advanced Industrial Science and Technology as well as at the Marie Curie Research Institute. He is, at present, the director at the Saravio Central Institute of Saravio Cosmetics Ltd. He has published a wide range of reputed journals, in Biophysics, Cell biology, Cosmetic science and so on.
Abstract:
We have investigated the fundamental functions of hair follicle cells along with microorganisms of the world famous Beppu hot spring spas. I would like to present how these unique spa-derived microorganisms affect the functions of human dermal papilla cells (HDPCs).rnHDPCs play essential roles in hair follicular morphogenesis and in hair growth cycles. We have discovered novel functions of mitochondria, an energy producing organelle, and primary cilia, a signaling center, in HDPCs. In brief, HDPCs showed two types of mitochondria, i.e. filamentous and rounded morphologies. PDGF-AA, an anagen-inducing growth factor, increased the population of the filamentous mitochondria and elevated cellular ATP level. Interestingly, the filamentous mitochondria dominated migrating HDPCs. By genetically modifying the length of the primary cilia, it was demonstrated that the sensory organelle is involved in communication with other cells through the regulation of growth factor(s) production. Additionally, bFGF elongated the primary cilia. Thus, HDPCs maintain the energy producing and the sensory organelles, as required. A spa-derived hydrolyzed yeast extract was found to enhance ATP production by increasing filamentous mitochondria and it augmented the strength of the cellular signaling by elongating the primary cilia of HDPCs.rnAlso, I am going to introduce our latest research on age-related hair problems: an advanced glycation end-product up-regulated the proinflammatory cytokines such as IL-1α, IL-1β, IL-6, IL-8 and TNF-α in HDPCs, which in turn inhibited the mesenchymal-epidermal interaction. Another hot spring microorganism (a green alga) suppressed the up-regulation of these cytokines, suggesting that the algal extract prevents the progress of age-related alopecias.rn
Keynote Forum
Donyelle McBride Rose
McBride Hair Restoration LLC, USA
Keynote: Hair loss management modern approaches
Time : 15:13
Biography:
Donyelle McBride Rose of McBride Hair Restoration LLC (MHR) is CT's first and only Trichologist office with an on-site Certified Natural Health Practitioner. The office is pre-certified with International Association of Trichology (IAT) and is an affiliate office of Hair Loss Control Clinic. Donyelle specializes in Male/Female hair restoration and has a passion for helping other. She continues to educate Physicians, Medical offices, and Licensed Professionals about Alopecia awareness and the alternative solutions. In addition to being a licensed cosmetologist, Donyelle is a Look Good Feel Better Consultant for the American Cancer Society and a member of American Hair Loss Council.
Abstract:
Donyelle McBride Rose of McBride Hair Restoration LLC (MHR) is CT's first and only Trichologist office with an on-site Certified Natural Health Practitioner. The office is pre-certified with International Association of Trichology (IAT) and is an affiliate office of Hair Loss Control Clinic. Donyelle specializes in Male/Female hair restoration and has a passion for helping other. She continues to educate Physicians, Medical offices, and Licensed Professionals about Alopecia awareness and the alternative solutions. In addition to being a licensed cosmetologist, Donyelle is a Look Good Feel Better Consultant for the American Cancer Society and a member of American Hair Loss Council.
- Track 7: Hair Care
Track 8: Style – Devices and Formulations
Track 9: Recent Advances in Trichology
Track 10: Modern Techniques in Hair Transplantation
Track 11: Hair Loss Management and Modern Approaches
Track 12: The Business of Cosmetic Dermatology & Hair Care
Chair
Meena Singh
KMC Hair Center, USA
Session Introduction
Meena Singh
KMC Hair Center, USA
Title: Hair transplantation in women
Time : 11:15-11:40
Biography:
Dr. Meena Singh is a board-certified dermatologist and dermatologic surgeon currently practicing in New York City and Kansas City. She attended Harvard Medical School, trained at the Mayo Clinic, and completed a surgical fellowship in New York City, in which she became trained in Mohs Micrographic Surgery, as well as cosmetic dermatology procedures, such as Botox, lasers, and fillers. She also completed a fellowship with the International Society for Hair Restoration Surgery under world-renowned surgeon Dr. Marc Avram, and was trained in all hair transplantation techniques, including strip excision and manual/motorized/robotic follicular unit extraction, as well as transplanting into scarring alopecias. She also specializes in medical treatments for hair loss of all types. Dr. Singh also has an interest in treating ethnic skin/skin of color. Dr. Singh has performed clinical trials in laser hair stimulation, as well as studies in hair transplantation for scarring and non-scarring forms of hair loss. She has also performed investigative studies on skin cancer in transplant recipients, as well as tissue engineering. She has numerous publications in many peer-reviewed dermatology journals, book chapters, and has been published in the New England Journal of Medicine. She is a reviewer for the Journal of Cosmetic Dermatology and the Dermatologic Surgery journal. She has had numerous TV appearances and her blog articles have also been published in online and print periodicals. Dr. Singh has also been featured on the cover of New York Times.
Abstract:
20- 30% of all women suffer from female pattern hair loss (FPHL) in the US. Society expects to see hair thinning and hairline recession in men; however, it is less socially acceptable when it occurs in women. Fortunately, most women can be aided with a combination of both medical and surgical therapies. Minoxidil is the only FDA approved treatment for at this time. In the majority of women, it stops progression of the disease and can rethicken hair. Many women with FPHL are candidates for hair transplantation. With the use of follicular unit transplantation with smaller 1-4 follicular unit grafts, very good cosmetic, natural-appearing results can be achieved. Consultation for hair transplantation with a female patient differs somewhat than with a male patient. Because of the nature of FPHL, the patient is often more concerned about the ‘see-through’ nature of the scalp, as opposed to regression of the hairline or loss at the vertex scalp. They have a more unpredictable donor area. They can demonstrate telogen effluvium postoperatively. In addition, it is important to perform a detailed scalp examination and consider further labs and potentially scalp biopsy to differentiate FPHL from telogen effluvium or scarring alopecias. In consultation, the patient should be made aware that net cosmetic outcome and density will reflect the amount of hairs transplanted minus the ongoing hair loss. In addition, placing the hairs predominantly in the frontal scalp, as opposed to diffusely spreading it throughout the involved areas will lead to a better cosmetic outcome. The main procedural consideration for the surgery is that transplanted hairs will be placed in between existing hairs. The talk will begin with a general introduction, review differences between females and males, as well as technical considerations. The majority of the talk will be case based.
Biography:
Omid Arjmandi-Tash got MSc degree in Chemical Engineering from the University of Tehran. Currently he is a Research Associate at the Department of Chemical Engineering, Loughborough University. He is carrying out a joint research with Proctor & Gamble, USA. He has already published around 10 papers in highly rated scientific
Abstract:
Hair care products are expected to wet well human hair, even when the hair is hydrophobic. Thus, wetting properties of human hair are very important, as they influence consumer satisfaction with the products. Wettability of a hair tress is an important characteristic. The wetting behavior of polymer solutions on hair is less studied than surfactant solutions. The wetting of hair tresses by aqueous solutions of commercially available polymers AculynTM 22 (A22) and AculynTM 33 (A33) has been investigated. Both experimental studies and numerical simulations of behavior of polymer solutions and foams on tresses of human hair has been investigated including drainage of foams produced from solutions of those polymers and interaction of foams with hair stresses are presented. Both A22 and A33 solutions demonstrate well pronounced shear thinning behavior. Initial contact angle of the A22 and A33 solutions on undamaged hair tresses is about 100 o. The A22 droplets remained on the hair tress after spreading for at least half an hour. However, a fast penetration of the A33 droplet inside the hair tresses was observed when advancing contact angle in the course of spreading reaches a critical value of about (60 o). Pure solutions of A22 and A33 have higher initial contact angle and longer penetration time on hair tresses compared with the solutions containing i-propanol or sodium dodecyl sulphate. The results demonstrate that wetting kinetics of the polymer solution on hair tresses drastically different depending on the formulation and can vary from a rapid imbibition to a spreading only.
Biography:
Dr. K. Ravi did Post graduate in Siddha system of Medicine in The Tamil Nadu Dr. MGR Medical University, Chennai, India and he has been selected by the union public service commission and appointed as a Medical officer in the Central Government Dispensary and promoted to Chief Medical officer and served 20 years and now working as Joint Adviser (Siddha) in the Ministry of AYUSH, Government of India, New Delhi. He has published and presented 11 papers in reputed journals and conferences.
Abstract:
Psoriasis is a common life long, genetic, autoimmune skin disease characterized by well circumscribed areas of thick, red, scaly skin and From the Greek “psoros” meaning “rough, scabby, itch. In Siddha System of medicine Psoriasis is termed as Kalanchakapadai.Psoriasis is very well treated in Siddha System of Medicine for so many years and found patient is very much relieved from the thick, red, scaly skin and the recurrence is very much postponed and the patient may also have normal skin for many years. Vetpali Thailam (777 Oil) is a boon to treat psoriasis Patients for getting relief from the unexplained sufferings of the disease.
Biography:
Manager of scientific department, research and development,biologist and biochemist at Cepigene. Her research focus on what causes the disorders on hair and scalp, hair loss and dandruff, and also Research on cosmetics products such as anti wrinkles and actives
Abstract:
Epithelial’s stem cells are located in histological area called bulge in the middle part of hair follicle between arrector pili muscle and sebaceous gland which their potential to differentiate to variety of cells such as chondrocytes, osteoblasts, adipocytes, melanocytes, etc., is confirmed via several researches; as well as there is non-invasive method to extract hair follicle to culture organ for isolation of its stem cells, regarding the effect of some ingredients such as different herbal extracts and growth factors on aforementioned stem cells proliferation makes them suitable for tissue engineering. If these cells keep their proliferation potential in presence of such ingredients it can be a step to use them instead of other mesenchymal stem cells derived from adipose tissue or bone marrow to supply the required cells in scalp and skin area as well as in medical cell therapy; in this research the potential of proliferation of human hair follicle mesenchymal stem cells (hHFMSCs) is evaluated before differentiation in presence of several compounds. Some hair follicle cultured for 7 days after isolation from the scalp of 3 men with average age of 35 years; the wells populated with cells which had the morphological appearance of mesenchymal cells thus they were selected and pooled after survey on their superficial markers via flow cytometry and their mesenchymal nature was approved; also their potential for differentiation to osteoblasts and adipocytes approved by real-time RT-PCR., then expanded for 7 days in 8 distinct groups in 24-well culture plates with stromal medium culture containing 10% FBS, the first group supplemented with 1 ng/ml EGF, 1 ng/ml bFGF and 1 ng/ml aFGF, second group supplemented with 1.5% aqueous extract of leaf of Rosmarinus officinalis, third group supplemented with 1.5% of aqueous extract of root of Althaea officinalis, the fourth and fifth groups supplemented like the second and third groups but 3% of abovementioned extracts, the sixth group considered as the negative control, the seventh group considered as the positive control 1 with 1.5% aqueous extract of Rosmarinus officinalis plus 1.5% aqueous extract of Althaea officinalis besides growth factors with the same concentration to group 1, the eighth group considered as the positive control 2 with 3% aqueous extract of Rosmarinus officinalis plus 3% aqueous extract of Althaea officinalis besides growth factors with the same concentration to group 1; the cells proliferation potential evaluated by BRDU Assay. The comparison of results showed that the rate of cell proliferation in first group was more than other, then the seventh and next was the eighth group then in order, fifth, third, second, fourth group and eventually the negative control. This study showed that aqueous Rosmarinus officinalis extracts may be able to regulate the out of control proliferation of MSCs which is very important to prevent scar and cheloide formation while using growth factors for wound healing. Key words: Mesenchymal stem cells, Human hair follicle, BRDU Assay, Wound healing, Scar.
Biography:
Adele has completed is Phd at the age of 26 years from University of Nigeria Nsuka and postdoctoral studies from Lagos University School of Medicine. He is the head of Department. He has published 17 papers in reputed journals he is currently serving as the head of board member of state medical council.
Abstract:
Encyclopedia of Bio analytical Methods for Bioavailability and Bioequivalence Studies of Pharmaceuticals (E-BABE). It is a unique encyclopedia involving bio analytical methods for bioavailability and bioequivalence (BA/BE) studies of pharmaceuticals for suitable method selection with thousands of combinations and searches against these methods. Most scrutinized literature was collected from different sources such as Drug bank, Medline, Pub Med. The bio analytical method assessment of the studied drug product, carried out in our laboratories, covers two aspects of evaluation. The first one is the drug in-vitro evaluation including conformity of drug active ingredient content and content uniformity employing official pharmacopoeia methods, and also the determination of the drug dissolution rate in accordance with the official methods. These tests were conducted to verify compliance of the drug product to applied quality standards. The second aspect involves biological or in vivo evaluation. This evaluation consists of microbiological assay for the label claim of the studied drug product, and development and validation of a suitable and reproducible bio analytical assay method to obtain plasma concentration-time profile. Data obtained to be employed for assessment of the drug product kinetics. Depending on the chemistry of the drug product, reversed-phase high performance liquid chromatography (RPLC) was chosen, as the analytical technique, in developing drug assay method, due to its explosive popularity for analytical separations. This choice was also due to many factors as will follow. The variation of element composition alone extends both retention and selectivity in RPLC over an extremely broad range of analytes. Practically all reversed phase separations are carried out on stationary phases with chemically modified hydrophobic surfaces. Minor variations in the surface chemistry and geometry can lead to noticeable differences in surface interactions and, as a result, to differences in chromatographic selectivity. Mobile phase (eluent) is by far the major “tool” for the control of analyte retention in RPLC. Variations of the eluent composition, type of organic modifier, pH, and buffer concentration provide the chromatographer with a valuable set of variables for successful development of a separation method. Mobile-phase pH affects the analyte ionization and thus its apparent hydrophobicity and retention. Most drug products may be ionizable, and therefore their retention is affected by the mobile-phase pH. The influence of temperature and type and concentration of organic analyte and pH modifier ionization are also related to HPLC retention. All the choices the biocatalyst has in terms of bonded phase, aqueous phase modifier, and organic modifier can have synergistic effects on the analyte retention and selectivity in RPLC. These parameters illustrating the power of the selection of the most suitable parameters for control of the analyte retention and selectivity, and therefore the choice of a better analytical assay method, in terms of the following validation parameters.
Biography:
Dr. Bharat Bhushan is an Ohio Eminent Scholar and the Howard D. Winbigler Professor in the Department of Mechanical and Aerospace Engineering. Dr. Bhushan came to OSU in 1991 after a 15-year career in industry, working primarily for IBM Almaden Research Center. A professor with diverse interests, Dr. Bhushan’s works in biomimetic interface science, surface engineering, nanotribology, and materials research. His research has focused on scanning probe techniques in the interdisciplinary areas of bio/nanotribology, bio/nanomechanics and bio/nanomaterials characterization and applications to bio/nanotechnology, and biomimetics. Dr. Bhushan spent the 2013-2014 year working as an ASME Science Fellow in Congress. His work there focused on policy and funding of various scientific government agencies, setting science and engineering goals for the country, and STEM education. Dr. Bhushan is a prolific author (h-index – 76+; ISI Highly Cited Researcher in Materials Science since 2007 and in Biology and Biochemistry since 2013; ISI Top 5% Cited Authors for Journals in Chemistry since 2011), influencing many different fields. He has authored 8 scientific books, 90+ handbook chapters, nearly 900 scientific papers, and 60+ scientific reports. He has also edited 50+ books and holds 20 U.S. and foreign patents.
Abstract:
Human hair is a nanocomposite biological fiber. Maintaining the health, feel, shine, color, softness, and overall aesthetics of the hair is highly desired. Hair care products such as shampoos and conditioners, along with damaging processes such as chemical dyeing and permanent wave treatments, affect the maintenance and grooming process and are important to study because they alter many hair properties. Nanoscale characterization of the cellular structure, mechanical properties, and morphological, frictional, and adhesive properties (tribological properties) of hair are essential to evaluate and develop better cosmetic products, and to advance the understanding of biological and cosmetic science. The tensile response of hair is of considerable interest. Another property of interest is the surface charge of hair, which has a significant effect on manageability, feel, and appearance. For this reason, controlling charge buildup to improve these factors is an important issue in the commercial hair care industry. The atomic/friction force microscope (AFM/FFM) and nanoindenter have recently become important tools for studying the micro/nanoscale properties of human hair. In this talk, we present a comprehensive review of the cellular structural, nanomechanical, and nanotribological properties of various hair and skin as a function of ethnicity, damage, conditioning treatment, and various environments1-2. Various cellular structures of human hair and fine sublamellar structures of the cuticle are identified and studied. Nanomechanical properties such as hardness, elastic modulus, creep and scratch resistance are discussed. Nanotribological properties such as roughness, friction, and adhesion are presented, as well as investigations of conditioner distribution, thickness, and binding interactions.
V Hari Kumar
Hair Transplant & Aesthetic Surgeon, India
Title: FUE -Hair Transplantation VS Combo Method
Biography:
Dr.V.Hari Kumar, MBBS, MS (Gen Surg.) (M.Ch Plastic) FIAGES, an Hair Transplant & Aesthetic Surgeon works as a Chief Consultant at B-Perfect Aesthetic Solutions, Banjara Hills, Hyderabad, India. He is an Asst. Professor at Deccan Medical College and passionately trains the Doctors& Surgeons in his self-chosen field of Creative Anti Ageing & Inner Cosmetics. He received Commendation Certificate (Best Doctor Award) twice during 2003-05 for his extensive Medico-Spiritual Holistic Health Service Activities to beautify not only outer but also inner Personality. He has authored three books & compiled 40 DVDs on Art & Science of Anti Ageing-Inner Cosmetics-Longevity-Holistic Living. His Enthralling & Energetic Live Telecasts & Debates in more than 30 Television Channels, on subjects like Medico-Spiritual Anti Ageing, Life Skills, Holistic Health helped many viewers especially Health & Success lovers.. His presentations in National & International Conferences and several Spirituous-Scientific publications add to his credit and are a Visiting Professor & guest speaker to many Organizations.
Abstract:
Hair restoration by Transplantation is the permanent, relatively safest solution for the baldness. Follicular Unit Extraction FUE,, being a scar less procedure is widely accepted and routinely done HT surgery by us. Easy recoveries, negligible pain, early resume to normal work are the noticeable benefits. Scar of FUT-strip method, presence of limited donor area due to final grades of baldness and previous surgery scars.. And also, in clients with tight scalp, keloid propensity, feasibility of hair from non-scalp hair bearing body areas are better suited for this procedure. Athletes, Clients of Medical tourism, who are with fear of pain & surgery, in case of OT assistant’s scarcity it works well.. Early stages of baldness requiring up to 1500 grafts are better candidates. High cost, need of high skilled surgeon, larger area of baldness requiring grafts more than 1500 are the limiting factors. BHT-Body Hair Transplantation where body and beard hair can be utilized for the crown and hair line design. Rest of the mid section and frontal forelock can be done with the permanent hair which is available from Hormone resistant existing safe donor area on the back of the head as a Day care Procedure. Combination of FUE & FUT Net yield will be more, extraction and surgeon’s time can be minimized, tension on the scar will be less and double &triple FU extraction can be done under vision. Number of sessions can be reduced and Trichophytic closure after strip favors the growth of hair on the scar line.
- Workshop
Session Introduction
Suzanne M Anderer
Suzanne Anderer:Illinois School of Electrology, USA
Title: S.I.M.P.L.E. (Sequential, Inverted, Micro-Pulse, Led, Energy): Needle - type permanent hair removal
Time : 13:40-14:40
Biography:
Suzanne Anderer is a nationally recognized expert in permanent hair removal. In 1982, she founded Suzanne Anderer: Illinois School of Electrology (SA: ISE), an Illinois Board of Higher Education approved institution. Four years later, Professional, National Board Certification from the American Electrology Association (AEA) was granted and Suzanne became a Certified Professional Electrologist (CPE).
Abstract:
The S.I.M.P.L.E. (Sequential, Inverted, Micro-Pulsed, Led, Energy) employs AC (alternating Current), at the standard AC current cycle level produced in the United States for delivery to Consumers. The definition of the acronym is the following: S is a sequential series of heating Patterns; I refers to an inverted application, each pulse point traveling downwards to the base of the follicle; M is for micro, or the small heating patterns used in the method; P is for pulse which references the quick bursts of energy; L is for led, or the action of micro-pulses traveling downwards, contacting untreated tissue; and E is for energy, a term used to define electricity which has a heat-producing effect. These currents are not a galvanic or “blend†current; therefore it is not electrolysis. In my lecture, I would like to expound on this particular needle-type application; it is a method with heat-producing properties and the distinct benefit of micro-pulse, radio frequency (RF) contact throughout the ENTIRE dermis of each visible, hair-producing follicle. Variables such as texture of hair, stage of hair growth, endocrine and drug-induced hair growth, and skin color and type are accounted for in this method. This method is minimally invasive with shorter recovery periods and less damage to surrounding tissue. When correctly applied, permanent hair removal has been consistently observed in one application per visible hair (references and client data will be produced to support this).